Topic
Nutrition in critical care
Route, timing, and dose of nutritional support.
No trial records summarised for this topic yet.
Key references
Guidelines, standards and reviews for this topic.
- Guidelines
- Singer P, Blaser AR, Berger MM, et al. ESPEN practical and partially revised guideline: Clinical nutrition in the intensive care unit. Clin Nutr 2023 Sep;42(9):1671-1689. PMID 37517372
- Taylor BE, McClave SA, Martindale RG, et al. Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). Crit Care Med 2016 Feb;44(2):390-438. PMID 26771786
Studies not yet summarised
On the reading list for this topic and awaiting a full record. Listed here so nothing is hidden.
- Practical Issues in ICU Nutrition
- Reignier J, Mercier E, Le Gouge A, et al. Effect of not monitoring residual gastric volume on risk of ventilator-associated pneumonia in adults receiving mechanical ventilation and early enteral feeding: a randomized controlled trial. JAMA 2013 Jan 16;309(3):249-56. PMID 23321763
- Davies AR, Morrison SS, Bailey MJ, et al. A multicenter, randomized controlled trial comparing early nasojejunal with nasogastric nutrition in critical illness. Crit Care Med 2012 Aug;40(8):2342-8. PMID 22809907
- Strategies for Nutrition in the ICU
- Summers MJ, Chapple LS, Karahalios A, et al. Augmented Enteral Protein During Critical Illness: The TARGET Protein Randomized Clinical Trial. JAMA 2025 Jul 22;334(4):319-328. PMID 40495743
- Heyland DK, Patel J, Compher C, et al. The effect of higher protein dosing in critically ill patients with high nutritional risk (EFFORT Protein): an international, multicentre, pragmatic, registry-based randomised trial. Lancet 2023 Feb 18;401(10376):568-576. PMID 36708732
- Arabi YM, Aldawood AS, Haddad SH, et al. Permissive Underfeeding or Standard Enteral Feeding in Critically Ill Adults. N Engl J Med 2015 Jun 18;372(25):2398-408. PMID 25992505
- Harvey SE, Parrott F, Harrison DA, et al. Trial of the route of early nutritional support in critically ill adults. N Engl J Med 2014 Oct 30;371(18):1673-84. PMID 25271389
- Rice TW, Wheeler AP, Thompson BT, et al. Initial trophic vs full enteral feeding in patients with acute lung injury: the EDEN randomized trial. JAMA 2012 Feb 22;307(8):795-803. PMID 22307571
- Casaer MP, Mesotten D, Hermans G, et al. Early versus late parenteral nutrition in critically ill adults. N Engl J Med 2011 Aug 11;365(6):506-17. PMID 21714640