Topic
Gastroenterology in critical care
GI bleeding, stress ulcer prophylaxis, and liver failure.
No trial records summarised for this topic yet.
Key references
Guidelines, standards and reviews for this topic.
- Acute Liver Failure
- Shingina A, Mukhtar N, Wakim-Fleming J, et al. Acute Liver Failure Guidelines. Am J Gastroenterol 2023 Jul 1;118(7):1128-1153. PMID 37377263
- Liver Disease
- Nadim MK, Durand F, Kellum JA, et al. Management of the critically ill patient with cirrhosis: A multidisciplinary perspective. J Hepatol 2016 Mar;64(3):717-35. PMID 26519602
Studies not yet summarised
On the reading list for this topic and awaiting a full record. Listed here so nothing is hidden.
- Acute Liver Failure
- Cardoso FS, Gottfried M, Tujios S, et al. Continuous renal replacement therapy is associated with reduced serum ammonia levels and mortality in acute liver failure. Hepatology 2018 Feb;67(2):711-720. PMID 28859230
- Lee WM, Hynan LS, Rossaro L, et al. Intravenous N-acetylcysteine improves transplant-free survival in early stage non-acetaminophen acute liver failure. Gastroenterology 2009 Sep;137(3):856-64, 864.e1. PMID 19524577
- Gastrointestinal bleeding
- Cook D, Deane A, Lauzier F, et al. Stress Ulcer Prophylaxis during Invasive Mechanical Ventilation. N Engl J Med 2024 Jul 4;391(1):9-20. PMID 38875111
- Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial. Lancet 2020 Jun 20;395(10241):1927-1936. PMID 32563378
- Young PJ, Bagshaw SM, Forbes AB, et al. Effect of Stress Ulcer Prophylaxis With Proton Pump Inhibitors vs Histamine-2 Receptor Blockers on In-Hospital Mortality Among ICU Patients Receiving Invasive Mechanical Ventilation: The PEPTIC Randomized Clinical Trial. JAMA 2020 Feb 18;323(7):616-626. PMID 31950977
- Villanueva C, Colomo A, Bosch A, et al. Transfusion strategies for acute upper gastrointestinal bleeding. N Engl J Med 2013 Jan 3;368(1):11-21. PMID 23281973
- Liver Disease
- Wong F, Pappas SC, Curry MP, et al. Terlipressin plus Albumin for the Treatment of Type 1 Hepatorenal Syndrome. N Engl J Med 2021 Mar 4;384(9):818-828. PMID 33657294
- García-Pagán JC, Caca K, Bureau C, et al. Early use of TIPS in patients with cirrhosis and variceal bleeding. N Engl J Med 2010 Jun 24;362(25):2370-9. PMID 20573925
- Sort P, Navasa M, Arroyo V, et al. Effect of intravenous albumin on renal impairment and mortality in patients with cirrhosis and spontaneous bacterial peritonitis. N Engl J Med 1999 Aug 5;341(6):403-9. PMID 10432325