Topic
Nephrology in critical care
Timing of renal replacement therapy and fluid choice.
No trial records summarised for this topic yet.
Key references
Guidelines, standards and reviews for this topic.
- Reviews
- Gaudry S, Palevsky PM, Dreyfuss D. Extracorporeal Kidney-Replacement Therapy for Acute Kidney Injury. N Engl J Med 2022 Mar 10;386(10):964-975. PMID 35263520
- Ronco C, Ricci Z, De Backer D, et al. Renal replacement therapy in acute kidney injury: controversy and consensus. Crit Care 2015 Apr 6;19(1):146. PMID 25887923
Studies not yet summarised
On the reading list for this topic and awaiting a full record. Listed here so nothing is hidden.
- Modaliaty and Timing
- Liu KD, Siew ED, Tuot DS, et al. A Conservative Dialysis Strategy and Kidney Function Recovery in Dialysis-Requiring Acute Kidney Injury: The Liberation From Acute Dialysis (LIBERATE-D) Randomized Clinical Trial. JAMA 2026 Jan 27;335(4):326-335. PMID 41201895
- Gaudry S, Hajage D, Martin-Lefevre L, et al. Comparison of two delayed strategies for renal replacement therapy initiation for severe acute kidney injury (AKIKI 2): a multicentre, open-label, randomised, controlled trial. Lancet 2021 Apr 3;397(10281):1293-1300. PMID 33812488
- Bagshaw SM, Wald R, Adhikari NKJ, et al. Timing of Initiation of Renal-Replacement Therapy in Acute Kidney Injury. N Engl J Med 2020 Jul 16;383(3):240-251. PMID 32668114
- Vinsonneau C, Camus C, Combes A, et al. Continuous venovenous haemodiafiltration versus intermittent haemodialysis for acute renal failure in patients with multiple-organ dysfunction syndrome: a multicentre randomised trial. Lancet 2006 Jul 29;368(9533):379-85. PMID 16876666
- Prevention
- Chanderraj R, Dickson RP, Sjoding MW. Cefepime vs Piperacillin-Tazobactam for Acute Infection in Hospitalized Adults. JAMA 2024 Feb 27;331(8):707-708. PMID 38411650
- Finfer S, Micallef S, Hammond N, et al. Balanced Multielectrolyte Solution versus Saline in Critically Ill Adults. N Engl J Med 2022 Mar 3;386(9):815-826. PMID 35041780
- Zampieri FG, Machado FR, Biondi RS, et al. Effect of Intravenous Fluid Treatment With a Balanced Solution vs 0.9% Saline Solution on Mortality in Critically Ill Patients: The BaSICS Randomized Clinical Trial. JAMA 2021 Aug 10;326(9):1-12. PMID 34375394