Respiratory Trials·org

Palliative care · Supporting families

PARTNER randomised trial

A Randomized Trial of a Family-Support Intervention in Intensive Care Units

PARTNER trial design and results
Design Stepped-wedge cluster-randomised trial
Treatment Family-support intervention delivered by the interprofessional ICU team
Control Usual care
Population 1420 critically ill patients and their surrogate decision makers
Follow-up 6 months
Primary endpoint Surrogates' Hospital Anxiety and Depression Scale score at 6 months
Result There was no significant difference between intervention and control in surrogates' mean HADS score at 6 months. The intervention improved surrogates' ratings of the quality of communication and patient- and family-centredness of care, and shortened ICU length of stay.
Secondary endpoints Quality of communication, patient- and family-centredness of care, ICU length of stay, mortality

Among critically ill patients and their surrogates, a family-support intervention delivered by the interprofessional ICU team did not significantly affect the surrogates' burden of psychological symptoms, but the surrogates' ratings of the quality of communication and the patient- and family-centeredness of care were better and the length of the ICU stay was shorter with the intervention than with usual care.

The trial authors, in the published abstract

How it has aged

Better communication did not reduce anxiety and depression six months on, which is a sobering finding for an intervention designed around exactly that. The shorter ICU stay is the concrete result, and it came from families reaching decisions sooner.

Publications

A Randomized Trial of a Family-Support Intervention in Intensive Care Units

White DB, Angus DC, Shields AM, et al. A Randomized Trial of a Family-Support Intervention in Intensive Care Units. N Engl J Med 2018 Jun 21;378(25):2365-2375.

  • No reduction in surrogates' anxiety and depression at 6 months
  • Better ratings of communication quality
  • Shorter ICU length of stay